We need more pictures as we can’t see the whole room.

First thing I would do is find another place for the tv.

Here are more pics. Guess I should have started with, help me design my room around teh fact that I have a big TV over the fireplace. It's a battle I can't win, although I can do just about anything else. This room is the center of activity in our home and often includes 10+ people watching sports.

It's too crowded, but if it functions as the man cave, I wouldn't worry about it. Find a quiet room somewhere else for your lady lounge and focus your efforts on some serenity. What would I do? I would eliminate so many big openings, especially the one into the kitchen. I would also replace the big sectional with a 3-seat sofa for more flexibility in arranging.

The sectional is too big for the space. You need furniture that's smaller in scale.