i am using large format tiles are 48x24 and will be placed stacked (not brick layout). if i buy the kohler vedera in 40 wide, the medicine cabinet and center it over a 54 inch vanity, it will end at inch 47 on the wall making the grout line just outside the medicine cabinet. is that a design no no in terms of aesthetics? will it be big eyesore?

my other choice is to go with a more expensive sofia medicine cabinet that is 48 inches wide that would put the grout line 3 inches before the end of the medicine cabinet (meaning the medicine cabinet will cover it.

thoughts?