Tempered glass for a stair railing does not go on interiors. That is an exterior product. So do not replace an actual wrought iron staircase with glass. No.

If you have a contemporary or modern space, the glass will look fine. If your house is traditional or transitional, glass could look out of place. Have you considered cables?

I did think of cable but I have a toddler who is a climber and our contractor told me that he has to tell about the dangers of her falling over.

"Tempered glass for a stair railing does not go on interiors."

capaul1, why not? It's done all the time....................

Acrylic is NOT acceptable for railings as mentioned above it will look awful in no time flat as it will scratch, and badly.