Take out wall tile and vanity.

The tile is actually could be a huge design piece. The sink top is a bit dated. search pink retro bathroom for ideas!

Gut if you can. If not replace tile and vanity and up date lighting. Lose the dark curtain. Update blind. Use same blind with a light color valance &/or sheer curtains.
Definitely replace the toilet!!! & conserve water. Elongated bowl/seat are very comfortable.
Consider replacing shower in same footprint with a glass enclosure.
A vessel sink on a footed cabinet would look very up to date.
Add some nice coordinated towels and wall art.
Home improvement stores have lots of reasonably priced choices.