Yes, it will probably look off. Get some white painter's tape to try out on the trim and crown molding. Then you can decide.

I usually love a crisp white trim but if your windows are cream colored white trim might just make the windows themselves look dirty.

Context is key. Post pics as the balance of the room needs to be considered as well as other factors, like natural lighting, floors, furnishings, etc., etc..

A lot depends on the windows and how much cream shows with window coverings .Post some pics her ein a comment

agree ^ white on white, cream, is often a great look, but what does the room look like?

Pictures please