No one's answered yet, so I'll give it ago. I have a long slope, ten to fifteen feet deep by I have no idea but estimate over 100 feet long. could be a lot more, I'm bad at estimating distances like this.

Anyway, it was once planted with periwinkle and juniper. Then neglected for years. This is our third year in this house and I finally got a handle on it. The weeds I had to deal with were: garlic mustard, weedy grasses, wineberry, poison ivy, bedstraw, queen anne's lace, dandelions, virginia creeper etc. I started by roundup brush killer on the poison ivy, virginia creeper, and winebery. In the beginning I was brushing it on the foliage with a paintbrush. I graduated into spraying as carefully as I could, cutting out any juniper or periwinkle I might have hit in error when it turned brown. I had a large area and became very impatient! And I pulled as many weeds as possible, sometimes I got roots, sometimes I just prevented reseeding.

This year, however, I really made progress. I went out there as soon as the ground warmed enough (March) and started pulling weeds. I pulled yards and yards of poison ivy and wineberry. Then, when the new growth started, I again used brush killer. I have SO much periwinkle that if I killed some it really didn't matter, it will fill in easily. It's still a work in progress and will take a few more years before I have it the way I want it, but at least it's no longer a sea of weeds.

Too late to try this year, for now I'd just get in there and pull. And use a pre-emergent so any weed seeds you disturb won't germinate.

Hope this was helpful!