I prefer one large rug perpendicular to the bed, going under the foot of the bed. I think it looks nicer and it also means that there is rug in front of the bed rather than just at the sides. But I think it's fine to do runners at the sides.

My Master:

I step onto the rug when getting out of bed.
{{!gwi}}

We also have a runner in the bedroom hall
{{!gwi}}

Guest bedroom

Have a rug at end of bed, and also a runner on the side

Did you ever decide on a rug(s)? Here's a handy "how to" on bedroom rug size.

Here is a link that might be useful: Bedroom Rug - how to select