Yes, you can use different crown, as long as they don't meet up, because the profile will not line up, other than that you OK.

How tall are your ceilings that you want to do a ten inch crown? Be careful of your door/cased opening areas, then. Tie it all in. Sounds like you are looking for a formal look?

Ten inches of crown is over the top unless you are talking about 12 foot ceilings. I see no reason to change molding profiles between two rooms that are near one another, or even sharing a hallway. Trim.....is one of the most unifying elements in a home. ...........thus, pick a pleasing size, style, and stick with it.

Oversized crown makes very little sense with skimpy window casing and base skirting. Be careful one doesn't make the other even more obviously lacking in scale.