Possibly sawfly (larvae) damage -- described here (scroll halfway down). If you turn over the leaves, are there any critters underneath?

I will look tomorrow. Out of town. So will the systemic insecticide help?

thanks

I would imagine so. It should be listed on the label, but sometimes it will work, but just hasn't been tested. However, I should mention since you may not have thought about it or even be aware, that systemics of this sort are very bad for bees. Absolutely no judgement if you choose anyway, but with just a few roses, they are easy to control. Here, unfortunately, we have the kind that are all summer long. Some places just have one period.

Sawfly larvea...Rose slug damage

Yep. It is rose slug damage. Because rose slugs eat from underneath the leaves, just make sure you spray the leaves from underneath.