Yes I do many kitchens with contrasting lower/upper cabinets. It can ground a space and make it appear taller, but some layout don't work well with this color blocking of cabinets.

Post a picture and maybe someone can Photoshop what it would look like.

I'm doing light uppers and dark lowers, this has been my vision for the new kitchen for 5+ years.

I've seen a lot of examples of uppers painted white with lowers wood or a darker color like blue, and it looks good. With the right backsplash it can make the uppers almost disappear and open up the space visually.

Thanks @Erin for the examples. I have seen a lot of examples with islands, but not as many without the island. Love the whites with gray lowers. I'll post a picture of the kitchen as soon as I get a chance.