I find that style od molding very difficult to use art with and honestly do not see what you would gain by doing it in that space . You seem to have a modern space and those moldings are traditional. I would add some drapes to the DR and maybe a different wall color.

Your balance is off.

The wall isnt that large, it is going to look cluttered with that many panels and the fact they are different widths.

Nix the small panel to right of window. Do two side panels (each side of center art panel) the same size as the one to left of window and expand the center one.

Your house looks somewhat contemporary for traditional panel moulding.

@Design Interior South please see attachment if this is what you meant. The wall is 21 feet. and you can see additional photo there is a beam sort of splits the dinning and living room.

@Patricia Colwell Consulting thank you for your advice. I will consider it.

@BeverlyFLADeziner thank you for your reply. Don’t worry about the furniture. Just consider aa a little upgrade when I list the property for sell. What do you suggest with wainscot setting.

Making a mess of that wall with molding is not a little upgrade for selling. Next owner would probaly rip it all off

For picture frame molding to be successful it's best installed in a traditional room with some sense of symmetry. It's also usually installed on the full wall like you see in the images below. It also includes a complementary base and crown molding.

Your room might be better served if the molding were installed below a chair rail and painted white to unify the room and offer a contrasting background fo any furniture you purchase. This solution also makes it easier to accommodate windows and art in the room.

Wait.....upgrade for selling? Trim out you post and call it a day. Trimming out the wall isn't going to help you sell the house. If you want to improve the house and add some character trim out your post and paint it white to match the color of your crown moulding and paint the wood you have on your ledge/opening as well.

If you really want moulding on that wall choose one that matches the style of your home or else it is just going to look out of place.

This is a way to LIMIT your buyer pool. Don’t think about it a minute more if selling. Waste of time and money. Buyers want to see quickly how their “stuff” will fit in. This will be a stopper.