Nope, you need a full 21" in front of a toilet for clearance. The cabinet would have to be shallower. I find myself wondering why you want a 30 x 32 inch shower and such a large space for a toilet. Unless this is a child's shower or your family are slim, they are going to find a 30 x 32 inch shower stall with two glass sides kind of cramped. Elbows or hands hitting the glass when they raise their arms. I would like to suggest that you consider putting the toilet to the right of the vanity, as JuneKnow suggests. Most US jurisdictions allow for 15" clearance from the toilet centerline. Then you could put in a spacious 36 x 48 inch shower and next to it install one of the 11" wide kitchen pull-out pantry cabs like this.

Rev-A-Shelf 448-TP51-11-1 448 Series 11"W by 51" Tall Pull Out - Natural Wood · More Info

You could also be a little skimpy-er with the vanity size, going down to 32 or 33 inches. In order to have more usable "counter" space at a small vanity, you can put a 3" deep shelf made out of the counter material or out of windowsill material above the faucet and below the mirror and you will be able to place an electric toothbrush there or to simply have a place to set things when grooming in the morning.

Where are the doors in this room?

Thanks so much! Very helpful. The designer labeled the area to the right of the vanity wrong. It's actually a 32X60" bathtub with a 33" glass wall. I'm replacing it, but don't really want to move it.

What do you think about using a very small toilet? I've seen 24" deep toilets. Would this look very weird? I'd like to keep some counter space in front of the toilet including counter top and open shelving below. Again, thanks for your thoughts and help. Linda

No, this bath would not meet code in most localities.

I suggest that you ask your designer to read The Illustrated Rules of Good Bathroom Design, then try again.

we bought a 24" deep toilet because we had a similar clearance issue and it has worked out perfectly fine. I had feared it was going to look miniature or out of place but it has worked out perfectly and gave us the space we needed.

There are people who install wall mount toilets where the tank is in the wall - i'd imagine the toilet looks even "smaller" in that case. I wouldn't worry about it looking weird.

I am not sure where the bathroom door is but could switch the shower with the toilet. A 30x32 shower won't allow you to bend to wash your feet.

"A 30x32 shower won't allow you to bend to wash your feet."

Why don't people actually read what's written?

"The designer labeled the area to the right of the vanity wrong. It's actually a 32X60" bathtub"

I would move the toilet and make your vanity 42 inches wide (with drawers on one side), if possible.

My question is: Are these exterior or interior walls? Where will the plumbing go? There will need to be plumbing vents inside the walls & the drains will need to tie in somewhere. Toilet needs 3" to 4" drain. Sink needs 1-1/4". Tub needs 1-1/2". Shower (without tub) needs 2" drain.

You can put a cabinet above the toilet (high enough that people will not hit their heads on it) for extra storage and a medicine cabinet above the sink (if there is no window there).

Karenseb's layout looks good, but you'd have to nix the cabinet on the opposite wall. But, like I said. You could have wall-mount cabinets up higher. You could get a double shower rod or use two separate shower rods & have towels hanging on the outside rod. You will also need to make sure the door does not hit the shower when it opens.

If these are all interior walls, you might try to do some "between the studs" storage that only sticks out slightly. Buys you a little extra space.