Verify if the setbacks are to the foundation or the roof eaves.

I tell my clients barn doors are a real bad idea unless they are on a barn.

I’d consider shifting the bedrooms to the exterior corners to benefit from windows on two sides, moving the closet/laundry/bathroom interiorly. Who will be using the powder room next to the garage? I wouldn’t want guests going through the kitchen and mudroom for the loo. Is it for people doing messy tasks outside, to avoid having them walk through the house?

It appears you have a prep sink on the island. Move it over so you have counter space to place things coming out of the fridge.