I guess I'm the GLP-1 expert here.

It really has helped women with PCOS and T2D. So, she should be able to get a prescription for it. Since she has T2D she would qualify for Mounjaro since it is for T2D and with the introduction of Zepbound for obesity, people will need to have a diabetes code for Mounjaro and it isn't really being prescribed off label much.

That being said, the medications are in short supply, especially specific doses. I've seen it referred to as the "non-Hunger games." The starter doses of 2.5 seem to be more readily available. But everything keeps being pushed back for the 5 and 7.5 mg, and it might be well into June before they are available. I have obesity, hypothyroid, and prediabetes and started in January. I did 2 months of 2.5, one month of 5 mg, and was ready to move to 7.5 when I couldn't find either5 or 7.5. We were even going up to Asheville and I called some of the rural CVS along the way and nothing. Since it's been almost a month without it, it is recommended to start over. I did finally get a 2.5 yesterday. I am also looking into compounding, which I said I wouldn't do, but I am going through a local reputable pharmacy, but even this will take at least 7-10 business days. Luckily, I've maintained this month off the meds, but hunger and food noise have ramped back up especially the past two weeks. I'm not going to take my dose until Sunday which works best for me. I've lost 10 lbs. since January which is a little on the lower side of what I see online. But it's working in combination with my healthy habits.

It is also wild that some people pay almost nothing, some people pay $25, and everywhere in between. I use the coupon and pay $550 per month since it is not covered at all by my insurance. Compounding will be about $400-450 per month and is not usually covered by insurance, but I'm paying out of pocket anyways.

If you use Reddit, look at the Mounjaro and Zepbound subs. There's a lot of helpful information and regional chats about availability.

I wish the CVS app had better real time information. There is really nothing else to do but call around, and it's unfortunate because the pharmacy workers are busy enough without getting overloaded with calls. Most pharmacies can check within about a 20 mile radius. Some people have had better successes with Walmart.

RN, I had to look up GLP1 and one of the meds is semaglutide. I’ve had T2 for almost 15 years & got it under control from 2017 until this past February when my blood sugar suddenly took a high spike. Adjusting my meds did nothing so he prescribed Ozempic. Insurance would pay half leaving me with having to pay $500/mo out of pocket. He hooked me up with a compound pharmacy, $125/mo. I’m now on the highest dose & immediately my numbers are better. Have your dd ask about compounding pharmacies.

It was the highest dose that showed a better improvement.

My physician prescribed semaglutide for me, and since it is not covered my Medicare she recommended a local compounding parmacy. She vouched for the pharmacy and shared with me she has many patients using it. In addition I called and spoke with a pharmacist who answered my many questions to my satisfaction. (in fact, he complimented me for doing my "due diligence") I mention all this only because there is sometimes a negative bias about compounding pharmacies.

The cost (in New Mexico) ranges from 125 a month to 160 a month, depending on the dosage. You might ask her endocrinologist about using a local compounding pharmacy.

A women in my strength class at the gym was just telling me she is starting Zepbound this week and it sure sounds like you need a lot of persistence and strategy to get it. She was able to find the starting dose at Walmart and with the manufacturer coupon, she paid $550. The doctor told her to wait a week to start, and then start looking for next month's refill, so that she has a week buffer at the end if it takes some additional time to get the refill/next dose. It's a shame that the manufacturers can't keep up for all the folks who need it.

While I don't have diabetes or other disease they might help, I am fascinated by them. I recently listened to a Diary of a CEO podcast on this subject that was super interesting. The interview subject is a man who wrote a new book about semaglutides and takes them himself. (Don't pay attention to the headline - they're always misleading and/or sensational, no matter the subject.) https://youtu.be/0YMnHNIuK3M?si=P5MahdeUBteoeTZe