IMO bathrooms are small and the fwer finishes the better I use 12 x24 porcelain tile for the whole bathroom floor and sher walls all of them too . Then just the same tile smaller for the shower floor . Are those doors for the shower ? You cannot have them and the whole space needs to a be awet room . The vanity has to be a wall hung so a wheelchair can be moved up to the sink any linen cabinet sitting on top of the counter pretty useless for someone in a wheelchair so usually one sink and towel storage where you have the other sink Make sure you read about ADA complint spaces before figuring out pretty tile which as I sai is not a great idea

Just use all one tile like Patricia said. The combination you're showing is too busy. Something uniform ages better, meaning it's less trendy. Accent tiles aren't as popular as they used to be. A neutral background tile will accommodate multiple different wall colors and you can add color with towels and art which can be changed when you're tired of the color scheme.

Everyone doesn't define handicapped accessible the same, unless you want truly HA, then as Patricia says, you need to consult the ADA rules. If you just mean you want a spacious low threshold shower with grab bars then what you're showing will work. If you're trying to accommodate a particular person with a particular disability then do that, but ask yourself whether what you're doing will work if the person's condition worsens. If you need grab bars in the shower then you probably need them by the toilet as well.

Thank you
Disregard the ADA aspect
The real question is tile combination
Some things have been altered from original plan

You are the one who said handicap accessible so now we are not worried about that???? The tile selection is not good there you go.

Pick one tile for the shower walls. Maybe use the ascot for the shower walls and use it as a baseboard floor border.

Thank you