I grow year round in my greenhouse. I grow mainly orchids. Hanging from the top. But also grow tomatoes and peppers. It's pure sand where I live in Florida so I grow everything in pots. If you have auto vent openers, an exhaust fan on a therostat and keep it watered its doable.

Ventilation alone will not prevent an enclosed greenhouse from overheating. You need shade and/or evaporative cooling as well. For vegetables that require lots of light, it's much easier to just grow them outdoors. I think you'd be better off with a tall fence. I used to have an 8' tall fence around my vegetable garden to keep the deer out. There was chicken wire to keep the rabbits out.

I have so many pests here that it makes it really hard to grow anything so, I am working on building a totally enclosed garden. It is in the planning stage right now but will be around 30' X 40' and totally enclosed using concrete blocks, steel posts and chicken wire.
It sounds like an enclosure may work the best for what you are trying to do.