Looks like a heavy infestation of Eastern spruce gall adelgid. I'm not sure how you would control these at this time of year since it looks like the adelgids have already exited the galls (the galls are brown).

If the galls were still green, I'd say pluck them all off now, then in the winter give the branch ends a good spray of horticultural oil. The oil will coat and kill the adelgids that are hibernating in the buds.

I researched this last year after I found these galls on my Norway Spruce and doing the above has seemed to work as I have not seen a gall since. Hope it helps.