Posting in the thread so it's easier to see and respond.

Hmm, let me try again.

Is the bedroom door movable to the right? That adds some options.

The biggest issue I see is that the toilet's smack dab in the middle of the room. That's the hardest fixture to move, plumbing wise.

Thanks for putting that into the post, I wasn't quite sure how to do that....I'm a newbie! To answer your question about the door, yes I can move it as long as it stays on that wall.

OK, what about this:

-Knock down the interior walls.

Option A (separate tub and shower, single sink)
-Move the door to roughly the center of the wall.
-put the toilet to the immediate left of the door, and the toilet above that (where the makeup area is now). That gives you ~3'x4' shower; not huge but you could make it pretty.
-put a tub to the right of the door, in the corner and extending under one window.
-put the vanity where the tub/shower is now, and put some built-in storage in that little corner bump-out thing.

Option B (combo tub & shower, 2 sinks):
-move the door to the far right
-put the toilet in a separate room where the tub/shower is now, with a door on the far right
-the toilet room wall is 3' long and then a 2' door. Put one vanity on the wall part. Put a second vanity across from it, on the lower wall
-Put a gigantic shower in the current makeup area. Door centered between the vanities.

I didn't pay much attention to your plea for minimizing plumbing movement. Sorry. :-) Just trying to work on practicality foremost.

Thanks weedyacres! I really like Option B. Not sure that my budget will like it, but maybe I'll see how bad the plumber's bill might be... In the meantime I am still open for other ideas that are less plumbing intensive :)