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Inflammatory Bowel Disease

18 years ago

One of our cats has had constant diarrhea for ages. She has also lost more than half of her original weight (she was a very overweight 15 pounds and now weighs barely 7 pounds). Her liver enzymes are also elevated. Our vet did exploratory surgery with biopsy of her intestines and liver to rule out cancer, and she was diagnosed with IBD with slight liver inflammation. She is on prednisolone, Denosyl, Fortiflora, and will be starting weekly B12 shots. Does anyone here have any experience with IBD and how to control it? The prednisolone initially works to control the diarrhea, but as soon as it is tapered off, it restarts. I tried a supplement called "Feline Calm" which helped a lot, but the vet is not comfortable with it and advised me to stop using it. I am afraid because she is just skin and bones though she eats constantly. The vet said her intestines can't absorb enough nutrients because of the inflammation. Any input, ideas or advice would be much appreciated.

Comments (13)

  • 18 years ago

    My vet thought that my cat (8 yrs old from a shelter)may have had IBD, because he couldn't find bacteria in her stool(still loose and stinky after 8 weeks of anti-biotic). We never got around to the biopsy, because her condition cleard up after putting her on:
    1) a soil based probiotic called 'Pet Flora"
    2)Slippery Elm supplements
    3)1 oz of canned pumpkin per day

    I assume that the Fortiflora is a pro-biotic? What is in the Feline Calm that your vet objected to? The company where I bought the Pet Flora sent me a bottle of something called Luxolite (100% benonite clay) that is supposed to work well to normalize GI function. I've not used it because my cat is OK now (but I still give her the supplements mentioned above), but you might want to check it out.

    LF

  • 18 years ago

    Hi LF, yes, Fortiflora is a probiotic. I've tried pumpkin mixed into her canned food, and she will not eat it. Re. the supplement, (which I mistyped, it is called "Feline Comfort", not Feline Calm) she really couldn't tell me exactly what she was objecting to. The supplement contains slippery elm, probiotics, and other stuff. Here's a link:

    Here is a link that might be useful: Feline Comfort

  • 18 years ago

    Hi Petra...yes, that is the same company where I bought the PetFlora. Since my cat had not been specifally diagnosed with IBD...she just had really bad BMs (no weightloss or vomiting), the guy I spoke to at Vitality Science said that the Pet Flora pro-biotic should be sufficient, so I never bought the Feline Comfort. However, I did (at my vet's suggestion)give my cat slippery elm (one of the ingredients in FC) supplements that I got at the health food store as well. I understand that some vets (like MDs)don't trust non Rx supplements,but if the supplement is helping your cat, I would ask the vet what he/she finds problematic. And ask about the Luxolite/benonite clay while you are at it...although your vet has probably never heard of it. Vitality Science sent me a free bottle along with instructions when I re-ordered the Pet Flora. There is a guy named Steve at their toll free number...he was very helpful when I called.

    I also took my cat off all dry food except for 1/2 oz a day of Royal Canin Rabbit (grain free). The other food I feed her is canned Wellness Chicken (she seemed at the time to have problems with turkey and beef), so the food she's been eating has no grains or soy. I know it is hard to tweak one cat's diet when you have four others.
    LF

  • 18 years ago

    LF, they sent a small bottle of Bentonite along with the Feline Comfort. I used it a couple of times, but the FC was working pretty well, so I didn't continue. Maybe the vet is concerned about a liver interaction with the Feline Calm, and that is why she does not want me to continue, I don't know. The ingredients really don't look like they would harm the liver. Baby definitely has IBD, the biopsy was conclusive. She has a lot of inflammation. I really hate giving her Prednisolone, especially since it's not great for the liver. The vet sold me something called Denosyl, which is derived from Milk Thistle, I wonder if straight Milk Thistle would be better for her. We have to find something that works, she is skin and bones.

  • 18 years ago

    I'd ask the vet why she is against the FC, especially since you saw improvement while your cat was taking it. Could be she's wary of it interacting with some of the other meds your pet is on.

    Pred will help the inflammation of her GE tract and it's worth keeping her on it until things settle down.
    I once had a dog with IBD and her liver enzymes skyrocketed while on the pred but later, as she was weaned down to a minimal dose her enzyme levels dropped to normal range.

    Work on finding a bland diet that she will eat..............no grains.

  • 18 years ago

    Hi Petra
    Have you tried pysllium? I think it has the same effect as pumpkin...to bulk the stool...and may be have more neutral taste that puss would accept in her food. I think Metemucil is available in an unflavored, unsweetened variety. I don't know how good a patient your Baby is, but would you consider force feeding her the pumpkin via a syringe? You'll know in a day or two if its worth the trouble.

    Please call Vitality Science and ask specifically if there are any ingredients in Feline Comfort that would interfere with your cat's RXs. I am fortunate that the one of the three vets in the office where I take my cat is familiar with non Rx treatments...and although she prescribes patent meds, is very open to treating with natural methods as well. Prednisone would have been the next step for Odessa if the other stuff hadn't worked.

    As your vet said...if the inflammation is indeed causing your cat to be starved of nutrients, then the first concern is administering anti-inflammatory treatment. I really can't understand how slippery elm (which supposedly coats the intestine)or digestive enzymes (which help breakdown nutrients)would interfere with the prednisone.

    LF

  • 18 years ago

    annz, she is eating evanger canned, no grains. Re. the pred, will give it to her for now, but it scares me. One of our other kitties came down with diabetes and requires twice daily insulin shots because of steroid treatments for asthma. Of course, right now there doesn't seem to be any other choice. I am also going to get Vit B12 shots from the vet and give those to her once a week for a while.

    LF, good idea, I will call and ask. And thanks for the Psyllium suggestion, I hadn't thought of that. I did try to syringe the pumpkin several months ago when it was first mentioned in a thread here, but she hates it so much, I don't want to stress her by forcing her if there is an alternative.

  • 18 years ago

    How is kitty doing on the B12 now

  • 18 years ago

    Go to yahoo IBD feline list. You'll get a lot of help there.

  • 17 years ago

    I'm dealing with this issue now and have one question.

    If your cats' liver enzymes are up due to use of pred and his appetite is off - how do you remedy that? I need him to eat so he will ingest his medicine but it's the medicine that's causing his appetite to wane. Whew - it's circular - LOL.

  • 17 years ago

    Luvdogs- Prednisolone almost always causes an increase in appetite, not a decrease. If you are mixing the medicine in the food, the taste of the prednisolone could be causing him to not eat.

    Cats don't generally get steroid hepatopathy, so I would be concerned that something else is going on with the liver. If he was a previously oveerweight cat who suddenly stopped eating, I would be VERY worried about hepatic lipidosis (fatty liver) causing him not to eat and causing the increased liver enzymes. Another possibility is cholangiohepatitis, which cats get for unknown reasons. Even in dogs on pred, only the ALKP should increase; an increased ALT is always a major concern especially in cats.

  • 17 years ago

    Meghane, Oh - someone on this thread (annz post i think) said that their animals liver enzymes "skyrocketed" when on pred and i saw that elevated liver enzymes cause appetite loss so that's what i was thinking. So liver enzymes don't go up when on pred?

    i'm getting a cbc on him on Monday to see what it says.

  • 17 years ago

    will repost as OP

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