Appears to be downy mildew. If the shoots are ripening i.e. turning brown, I wouldn't worry too much for this year.

Bill, thank you. Do you know of a cheap and good product against mildew?

Copper, if you are organic. Captan, if traditional. I use both products in rotation. You are pretty much done for the year at this point. In the spring remove any fallen leave from around the trunk and spray/dust with fungicide every 7-14 days, (depends on material, read the ladel). Start at 1-3" shoot growth.

Bill, very useful and clear advice. Will do it on spring. This is a rkatsiteli vine, an old variety that I brought from Georgia (Imereti county). I will try making some good qvevri artisanal wine for home consumption. It has small leaves and it is a true pest, it will grasp everything around it with its numerous tendrils.