If you're washing a patchwork quilt, definitely Delicate and cool to cold water. Comforters, depends on construction and fiber. But, as you experiment with the cycles, use the one that fills with the most water and has a medium wash action (for sturdy poly fill and some down). Warm water of at least body temp helps to emulsify body soils. Detergent according to fiber and adding about 1/4c ammonia is my go to.

Yes, Delicates for your fragile blankets and quilts. I'd probably use warm water because modern machines have reduced the definition of warm water to 75F on some cycles. But you can also use Cool just to be sure.

I'd also use Extra Rinse because sudsy water isn't spun out after the wash and in between the rinses on Delicate - well, at least on my Duet.

Low or Medium spin, depending on the fabric and whether you want to put it in the dryer afterwards.

Delicates is a decent cycle for fragile or knit blankets. I would, however, give the colorlast cycle a shot with more sturdy blankets using warm. Supposedly it is designed to be more gentle and caring versus the normal cycle. We have lots of fleece blankets and I always use whites on them. It removes dog hair and doesn't tangle them up.