1/2 a cup of chartreuse? 40 - 50% abv. No wonder it perks you up!

Taking comfrey internally on a daily basis is a recipe for potential severe liver damage.

"The pyrrolizidine alkaloids contained in comfrey include intermedine, lycopsamine, symphtine and echnimidine, which are metabolized by the cytochrome P450 enzymes into highly toxic pyrrole metabolites which have alkylating properties that can damage hepatic endothelial cells and can cause sinusoidal obstruction...Hepatotoxicity from comfrey is now rare, as it is widely accepted as being toxic when taken internally and oral formulations are restricted or banned in most countries."

https://livertox.nih.gov/Comfrey.htm

floral_uk: So you can get perky on a tablespoon of Chartreuse? Guess you're staggering after a can of beer!

rusty_blackhaw: Do you have any idea how much comfrey you would have to take, and how often you would have to take it, to reach the level needed for harmful effect? Just because the NIH and FDA issues some edict does not make it valid. I find it laughable such governmental agencies are so concerned about getting comfrey, mercurochrome, etc., off the market, yet so unconcerned about potentially poisoning the food supply with GMOs, mercury-amalgam in teeth fillings, and so on. Let us not forget that the FDA has unleashed a host of nasties: Thalidimide, Fenfen, Fosamax, to name a few....and I am betting there will be many more to come.

Nearly ALL of the studies on comfrey are bogus. The primary study that puts a cloud over comfrey was where 6 month old rats were fed comfrey as 30% of their diet for an extended period of time. Unless you plan on taking it as 30% of your diet and have a rat sized liver............ anyway, more FDA attempts to make perfectly good medicine that THEY cannot control look bad.

We have been using comfrey in our herbal practice of LOTS of years with no limits and have seen no harmful effects from it.

As a precaution, we do not use it internally for pregnant ladies, small children or people with known liver issues.

There are no problems using it externally and some of the benefits can still be obtained in that method.