Many would turn to glyphosate herbicide applications for this, you can buy various products containing this active ingredient that are premixed if you don't want to buy and mix the concentrate yourself.

Be sure to keep the spray drift off of the shrubs when applying. A way to be sure of this is to hold a piece of cardboard between the shrub and the weeds being sprayed near it.

Ok, do you mean Round Up?

Same active ingredient but various other products are on the market that contain it also - you don't have to buy something with that particular trade name on the container to be getting glyphosate.

RoundUp is just one brand name. Glyphosate is sold under many others (and often cheaper than RU).

Is there a way to effectively paint it on the the weeds right next to the plants so I don’t have to worry about any unwanted contact?