Use only three sizes. Throw the rest in the donate bag. Put lids in one drawer, containers in another.

Nest.

We stack all the Tupperware containers by size and place each set beneath the corresponding stack. Works pretty well. I also put very small containers inside a larger, rectangular one that isn't used as often, to keep them from getting tossed about.

My son has a large drawer designated for the many containers they use with the squares stacked and the lids stored in a larger empty container. It works for them. I do what J. Alexander does in a smaller drawer (not many containers)