Whatever option you choose I would prefer a variable speed air handler model number AEPF4260 (or AEPF3036).

indy

I would go with one system and use zoning controls for two zones.

I would recommend a two stg HP with var speed air handler.

I would want an HVAC dealer with demonstrated experience with zoning and controls.

I would not recommend Goodman-sorry my prejudice.

IMO

You will be much more comfortable with 2 separate heat pump systems instead of one zoned system. The 2 systems will do a much better job of evening out the temperature differences between floors. You will notice this difference especially in the summer when the temperature difference tends to be about 4 degrees or so between floors. The system for the upper floors should run longer in the summer, reducing humidity as it runs. You also have no zoning controls involved with 2 systems. Zoning design can be challenging to an HVAC contractor.

The question is are you willing to pay $1500 more for 2 systems?

The key to your satisfaction is a good installation. A properly installed Goodman should outperform and outlast a poorly installed Trane or Carrier.

Your SSX 410 heat pumps have a lifetime compressor warranty, part-only, to the original purchaser (you).

Consider a separate 4 inch media filter cabinet for the air handler, as Goodman's filter rack for a 1" filter is poorly designed.

I agree with Ryan. In your Georgia climate, I would want at least one of the air handlers to have a variable speed fan (AEPF model numbers). V-S fans are quieter and can be set-up to reduce humidity better.

Good luck.

If you go with 2 separate systems, and one of them fails, you still have one functioning HVAC system for heating or cooling the home. No emergency HVAC situation because you have an option. Options are good.

Also, you are not paying twice the purchase cost for 2 systems. The 2nd system is $1500 more. Not bad.

i would a do a 5 ton goodman 410A heat punp because it is a 2 stage heat pump with honywell zone control and honyewell 8000 t-stats with dehumidity control, with variable speed fan,your your cost less to heat and cool my 2 story house is the same temp all over the house that is why you put a zone system in and a 2 stage heat pump so if 1 zone is call cooling it runs 1 stage of the heat p ump it is the cast of a 2.5 in the main floor it is a little big but if it is hot or humidity it will pull your house to your set temp

I wouldn't do a 5 ton if the house's load didn't amount to 5 tons. Low stage on scrolls is about 75% total, so that's about 3.75 tons when stage one is calling for a given zone. May be too much and cause short cycling, higher humidity, and higher electric bills.