Yes probably but it will look awful

sure.. you can do anything you want ...

but for each piece cut .. there will be.. probably.. 2 to 4 new shoots triggers.. AT TEN FEET ... and that will become a problem ...

how about a pic ...

google: REJUVENATION PRUNING OF SHRUBS ...

and that ought to get you where you have to go ...

its a 3 year process ... so if you did want to cut out one third per google .. and then top the rest ... maybe take down the second one third in fall ... and the last large part next year ... you can renovate the shrub back down to manageable size ...

but that all speculation.. w/o seeing your plant...

i doubt there are many Vs .. that you can kill by pruning.. that really isnt an issue ... but do understand.. that with no insult to the very mature root mass ... its going to react by growing like mad .. crazy mad ... insane mad ... and you really dont want that up at ten feet ...

ken

ps: have you thought about how you are going to go to town on it at 10 feet ???? this doesnt sound like it would be easy on a typical home owners 8 foot ladder ... lol.. i have had many great plans scuttled by physics.. lol ...