Hi Sherri! You could do a full on the top, and queen on the bottom. It would still work functionally. However, there would be less of a contrast in the depth between the top and bottom. Simply because a full and a queen are close in size, so they're not the same size difference that is achieved with a twin and a full. I hope that makes sense! Thanks for your inquiry!

Queen size bunk beds have become so popular. A queen size offers just few inches more than a full size, but surely adds to the comfort for two people. Totally Kids fun furniture & toys offers sever configurations of queen bunk beds. http://www.thebeanbagstore.com/bunkhousequeenbunks.htm