I don't think it would be weird at all. If you make them proportional it will look very custom. The beauty of an edge pull is that it really doesn't show *much*. I'd just go for it.

Oh I don't think it would look odd at all, in fact I think it would look odder if you had a 3" pull on a 36" drawer. Here's what I would do: cut out some thin cardboard in the different dimensions and place them on the top of each drawer and see how it looks proportionally...you may find you can easily get away with just 2 sizes, or you may find that all 3 look perfect, but mock it up first so you can envision it and how they will look together. Also you mention it's 2 different rooms...if they're completely separate and not just one big room flowing together then you don't have to be as concerned with consistency as much...you want the pulls to match of course, but you won't notice the sizing difference at all if in separate rooms.

Great suggestion! Thank you.