I would definitely not tile the entire room - it would feel like a hospital/operating room to me.

Personally, I like option one the best.

But not loving the sinks with backsplashes.

I assume that you meant to type that you don't love not having a backsplash for the sink(s). I would just use a piece of your countertop material for a backsplash behind the vanity. You could make it taller than the typical 4" piece + mount the faucet on the wall.

You could also add a little shelf above the the backsplash piece:

Here is one that is even taller with wall mounted fixtures. Also, the thick mitered edge used for the countertop looks nice.

Here is floating walnut one with a little higher piece used for the backsplash - but the fixtures are mounted on the countertop instead of wall mounted.

Here is a walnut floating vanity with solid white quartz (or corian) used for the countertop + backsplash.

Here is another walnut floating vanity with a higher backsplash piece + a skinny ledge/trim to finish the top off before using a large mirror over it. The skinny ledge/trim piece looks similar to the skinny/slim shaker drawer fronts.

This one has a white oak backsplash piece that matches the vanity - you could do the same with walnut. I assume that it's been sealed with some waterproof top coat (maybe like what is used on boats?) or it may just be water resistant.

Here is one with large format white tile used on the wall behind a floating vanity - personally, I don't like this one as much as the other examples - but you might:

Thank you so much for your insights and visual examples. I’m liking the wood backsplash if I can find a match or

May need to spring for the higher quality sink to get material nice enough looking to have extend up the wall.

Those embedded types are what I meant when I said I don’t usually like sinks with backsplashes.

We’re moving fast on this project so will circle back with pics soon! (Sorry for the multiple posts- app is being wonky)