Floor plan please. The answer depends on nearest full bath/nearest room to need a full bath to the proposed new location, and overall layout.

Without seeing the plan, I'd go with the large laundry IF you have another shower in the same floor. I prefer visitors to use a powder room.

It also depends on your family needs etc. For example, I am getting up there in age and it's just DH and myself so we don't generate a ton of laundry. Our laundry is going to be in a laundry closet and that works fine for us.

However, if I still had young kids where I was doing laundry several times a week, I'd want more of a room

Also depends on the type of laundry you generate. I hang at least half of all the laundry I wash so I need a large laundry room to accommodate it all.

Yup, depends on what you need. We are building a 2 story home with laundry on the main floor, but I need a 'clean room' to decontaminate from pet dander as soon as I get home from visiting friends (my husband is anaphylactic to most pets), so for us, the larger bathroom is preferred. Also look forward to using it to clean off after playing in the mud (garden!)