Sophie’s right, this is a challenging space, and it’ll take a creative expert and a substantial budget to make it the best it can be. The low, partly sloped ceiling and the location of the door limits your options, and makes the square footage functionally smaller.
If you’re hesitant to spend money on professionals, I’d make some careful measurements , draw it on graph paper, and sketch out some ideas. Be as accurate as possible with the size of the toilet, bed, closet depth, etc, so your sketch is realistic. This exercise may give you a sense of what’s possible in the space & whether the investment is worth it to you.

You definately need some help to make this odd space workable

Thank you everyone. Yes, when the time is right I will definitely need to hire an architect. Here is something I was working on. It's not to scale as I will need to really measure and be accurate. The open area when walking into the room will be a glass desk, storage room for office supply, file cabinet and printer. All doors have frosted glass barn door sliders. The bathroom has large shower, vanity and toilet. The closet wall where the wall is super pitched will just be short shelves or draws and the other side is all for hanging clothes. Your thoughts and input would be appreciated.

like mentioned above.

Sorry, you had me at lagoon...

I think this option will be cost friendly with less plumbing and demolition work.. Plus it will allow me to have a tub. The odd shape in the ceiling will give the bathroom character. Any thoughts?