Do you know how this wall was built? Do you have any photos of it before the tile panels were installed?

Frame TVs don't weigh as much as the old Plasma TVs, but ideally you would have installed blocking before the drywall was installed. If you don't have any blocking, the right mounting anchors can make it work.

What is behind the fireplace? Hopefully a closet? If it is, you can run the One Connect wire, through the wall and place the One Connect Box in the closet. You will probably need to cut a good size hole in the drywall in the back of the closet so you can access the space behind the fireplace.

This is my 75" Frame TV in a built-in wall unit. I also have a 3" aftermarket art frame on it.

The User Manual describes how the TV must be protected from heat and how the One Connect box must be oriented.

I installed a MantleMount TV bracket over my fireplace. It lets you bring the TV down lower if you want and angle it. I did not have stone or tile above my fireplace. They give you paintable panels to hide the hole. You could do the same with the tile, particularly if you have extra. As someone suggested, a closet behind that wall would make everything a bit easier.

Thanks for the comments. Yes there is a closet behind the fireplace. I've decided to route the cable into the closet, add power and store the one connect box in there. This would also be a good place to place audio equipment for in-ceiling speakers too. Got a guy coming Wednesday :)

"in-ceiling speakers too"

I assume you'll be using a sound bar or other speakers that face the viewer, and are using ceiling-mounted speakers for surround sound.

https://www.crutchfield.com/S-hQgXmolduM3/learn/speaker-placement-home-theater.html

@chispa - I didn’t know that they had after market frames for the Samsung Frame TV.

I really wanted a Samsung Frame - that was my requirement for a 75” tv. HOWEVER - my SO bought a 75” LG Gallery something - great picutre - he was told by the sales person that it was equivalent to the frame - but better picture (deeper blacks/hues or something).

But it is not the same - while the LG has a great screen + can be mounted flat against wall + the art looks nice, the art has to rotate vs. keeping the same art on screen (something to do with the type of screen).

That is not the same thing at all. NOT HAPPY. 😠

I'd find a different location for this very large TV screen.

@BeverlyFLADeziner Thanks for mocking that up, however the dimensions are not fully to scale. The panel width is 64.5" and the TV width is 57.25" leaving a 3.625" border either side of the TV. It looks good in my opinion, and it won't look like a big black screen, it'll look like a large hanging picture. Plus there are no other options for the TV.

@wdccruise A wall mounted sound bar isn't ideal as it takes away from it looking like a picture frame. Would you recommend any other options? Perhaps a white soundbar that's ceiling mounted and facing towards the viewer?

I don't have a sound bar on my frame TV, because this is not our main TV and I wanted it to look less cluttered and more like art. The sound from the internal Frame TV speakers is perfectly fine for everyday viewing.

@dani_m08, what I also like about The Frame TV is that the screen is matte, so you don't get glare on the TV and the art looks more realistic. We have big sliders in this room so not having glare makes a huge difference. True, the Frame TV does not have the best quality picture when compared to some other TVs, but this isn't our main TV, so that wasn't as important for me.

The aftermarket frames are pricey, but I'm really happy with the look. Very easy to put together and install. It came from decotvframes.com .

"A wall mounted sound bar isn't ideal as it takes away from it looking like a picture frame. Would you recommend any other options? Perhaps a white soundbar that's ceiling mounted and facing towards the viewer?"

"The sound from the internal Frame TV speakers is perfectly fine for everyday viewing"

Unlike @chispa, I would not be satisfied with mediocre sound after having spent $1500 on a 4K TV. Think about how the experience is enhanced with you go to a movie theater with both excellent picture and sound. CU tested the Samsung QN55LS01B (aka Frame) and its sound was only mediocre (score: 3 out of 5).

• One soundbar to consider would be the Samsung HW-S801B/ZA soundbar and subwoofer which received a "recommended" rating from CR and is on sale at Amazon for $450. It is extremely thin and can be hung on the wall (below the TV, not near the ceiling). It is even pictured with the Frame.

• Another options would be the small Sonos Beam Gen 2 and also can be attached to the wall.