yes. I have concrete. it was slightly sloped over the threshold so that the adjoining higher floor would be an easy transition.

if you can't do this, then get a transition piece for the threshold.

you may be able to get one in concrete and stain it to match your existing floor.

Schluter TK Reno is a transition profile piece too

tile on right, lower floor on the left. Orange is the Transition piece

Or, check to see if the tile you're using comes in any edge finishing pieces.

Oh sure! Keep in mind it will be cold-even though concrete is probably cold too, lol. There are lots of nice transition pieces that will work.

You can also do LVT-with a lower profile than tiles, which would probably be more ideal and warmer :)

Send pics when you decide. Taking a trip to a flooring co (not HD, etc) will educate you much more before doing something you may not be happy with after its too late

Good luck :)